Agrobacterium: From Biology to Biotechnology by Tzvi Tzfira,Vitaly Citovsky

By Tzvi Tzfira,Vitaly Citovsky

Agrobacterium is a plant pathogen which reasons the “crown-gall” illness, a neoplastic progress that effects from the move of a well-defined DNA section (“transferred DNA”, or “T-DNA”) from the bacterial Ti (tumor-inducing) plasmid to the host phone, its integration into the host genome, and the expression of oncogenes contained at the T-DNA. The molecular equipment, wanted for T-DNA new release and delivery into the host telephone and encoded by way of a sequence of chromosomal (chv) and Ti-plasmid virulence (vir) genes, has been the topic of various experiences during the last a number of a long time. this present day, Agrobacterium is the instrument of selection for plant genetic engineering with an ever increasing host variety that comes with many commercially vital vegetation, vegetation, and tree species. moreover, its fresh program for the genetic transformation of non-plant species, from yeast to cultivated mushrooms or even to human cells, offers this bacterium a different position sooner or later of biotechnological functions.

The publication is a finished quantity describing Agrobacterium's biology, interactions with host species, and makes use of for genetic engineering.

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